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Articles in periodicals and books Abstract: There is increasing amount of evidence for sex variation in drug efficiency and toxicity profiles. Women are more susceptible than men to acute liver injury from xenobiotics. In general, this is attributed to sex differences at a physiological level as well as differences in pharmacokinetics and pharmacodynamics, but neither of these can give a sufficient explanation for the diverse responses to xenobiotics. Existing data are mainly based on animal models and limited data exist on in vitro sex differences relevant to humans. To date male and female human hepatocytes have not yet been compared in terms of their responses to toxicants.Contributor, North, Bobby (Depicted). Type, Image. Note, Title of Larger Work: The Gay Hussars. Score KB application/pdf. Preview; Download. Title: Sex Differences in Liver Toxicity—Do Female and Male Human Primary Hepatocytes React Differently to Toxicants In Vitro? Authors. The first volume of this interesting collection of anecdotes and descriptions, very improperly entitled an History of the Female Sex, was published in ..the end of the story look at the video above ↑ ↑ ↑

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